You're thinking about introducing a mutation that alters the pathology of the virus. Keeps it from generating heat, consumes the extraneous energy. It's a difficult proposition. Heat is sort of the natural biological by-product of... well, all organic energy-use. [a bit amused, and then] If the functioning of prostaglandin E2 on the hypothalamus were...

[a beat, trailing off]

Could really go for that whiteboard right about now.